Amphetamine-Related Psychiatric Disorders StatPearls NCBI Bookshelf

May 12, 2020

Schedule a time to take it every day and stick to that same schedule for the duration that you’re taking the drug. This could feel like a “rush” or a euphoric feeling that makes you happy and elevates your mood. This sensation is something that can cause addiction because people might look to feel that rush more often than they should, as prescribed by their healthcare provider. Talk to your healthcare provider about the medicines and supplements that you’re currently taking before starting amphetamines. You will also want to regularly meet with your healthcare provider while taking prescribed amphetamines so your provider can observe their effectiveness in reducing your symptoms and monitor your dependency on the drug.

  • In nine of the studies reviewed here (20.9%), women were excluded by design.
  • The phrase “amphetamine salts” refers to the mixture that makes up generic Adderall.
  • Some very severe findings may include increases in systolic and diastolic blood pressure, tachycardia, dysrhythmias, hypertensive emergencies, and stroke.

The most common method for analysing UDS was weekly proportion of AMPH/MA-free UDS, or overall proportion of AMPH/MA-free UDS. There were 75 distinct secondary outcomes inclusive of variations and often analysed differently to the primary outcomes of the same domain. The most common secondary outcome measure reported was craving (25 times), predominantly reported using the visual analogue scale (VAS) (16 times, 64% of the cravings measures).

Types of Amphetamine

Martinez, who has been in recovery for two years, now works with a Washington, D.C.-based group called HIPS helping others with meth addiction. She says when she started her recovery, it was hard in part because there were no medical treatments to help with cravings and withdrawal. This new medical treatment strategy arrives at a time when addiction to methamphetamines has come roaring back, fueled by cheap imports from Mexico.

Data were extracted independently by the authors onto data extraction forms. Again, if disputes arose, these were resolved either by discussion between the two reviewers or the correspondence author of the paper. For this update of the review, one author (UK) inspected the search hits by reading titles and abstracts. Each potentially relevant study located in the search was obtained in full text and assessed for inclusion independently by two authors (SS & UK). Mixing amphetamines and alcohol is unsafe, as is mixing Xanax and Adderall.

Substance Abuse Treatment

Similarly, dependence to other substances such as alcohol, benzodiazepines or opioids is also likely to impact upon the safety and efficacy and choice of medications. Other comorbidities that continue to be poorly addressed include the management of patients with stimulant dependence and comorbid attention-deficit hyperactivity disorder (ADHD). Accurate diagnoses of ADHD in the context of AMPH/MA use can be complicated [82], and there may be differential effects of medications in patients with both conditions. More research is required regarding pharmacological responses for patients with ADHD and stimulant use disorders.

Misusing or taking amphetamines that your provider did not prescribe to you can cause dangerous side effects and could lead to addiction or death. Amphetamines rank as a schedule II/IIN controlled substance (2/2N), which means that there is a high potential for the drug to cause physical dependence (addiction). If you’re dependent on amphetamines and are taking more than the required daily amount prescribed by your healthcare provider, you shouldn’t breastfeed (chestfeed). Talk to your healthcare provider if you become dependent on any drug you are taking. Both amphetamine and methamphetamine are stimulant drugs that have different effects on your body based on the chemicals that make up each drug.

Amphetamine Addiction Treatment Levels of Care

While there are promising candidates, no pharmacotherapy for the treatment of AMPH/MA dependence/use disorder has provided convincing results. Studies are often limited by small sample sizes in defined populations, and with low treatment retention or completion rates. Different treatment options may be indicated for various degrees of severity of disorder. Optimal psychosocial interventions accompanying medication must also be considered. Further and substantial investment to determine effective pharmacotherapies is required. Conducting a traditional systematic review and meta-analyses is predicated on the assumption of studies reporting on similar outcomes, using similar outcome measures, and with similar methodology.

By the time a person realizes they are overdosing, it may be too late to get help. In many tragic cases, a person dies before they know that they were in danger. Amphetamines are drugs that make people feel awake and alert and can create euphoria.

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  • For the first time, a medication regime has been found effective for some patients with meth addiction in a large, placebo-controlled trial.
  • The authors note that further research is needed to identify how to best expand access to affordable, evidence-based treatment for adolescents with opioid use disorder.
  • METH comes in different forms and can be smoked, inhaled, injected, or orally consumed.
  • The destructive properties of these drugs make people who abuse them feel depressed and even suicidal when they are not using the drug.

The reported effect sizes and/or p values were considered as effectiveness of a treatment. A small effect size was considered as 0.2–0.49, a moderate effect size was considered as 0.5–0.79 and a large effect size was greater than 0.80 [13]. Due to the limited number Amphetamine Addiction of included studies, calculating effect sizes was not feasible. Outpatient substance use treatment emphasizes involving families in the recovery process. Family therapy mends relationships, fosters open communication, and educates loved ones about addiction.

As you embrace outpatient treatment, recognize that transformation is a gradual process. Use this time for self-discovery, understanding the roots of your addiction, and identifying the triggers that may lead to relapse. Engage with the therapeutic process with an open mind, allowing the gradual transformation to shape a new, substance-free identity. At Providence, you’ll have access to a vast network of dedicated and compassionate providers who offer personalized care by focusing on treatment, prevention and health education.

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